WHAT IS MERKEL CELL CARCINOMA?
Merkel Cell Carcinoma (MCC) is the rapid and uncontrolled growth of a collection of specialized skin cells (Merkel cells) that forms into cancer. It is a rare type of skin cancer that tends to grow quickly and has a high likelihood of metastasis (spreading to other parts of the body) compared to other types of non-melanoma skin cancers. Approximately one third of MCC patients will develop metastatic disease.
Despite being a rare form of skin cancer, Merkel cell carcinoma is the second most common cause of skin cancer death after melanoma.

What are Merkel cells?
Merkel cells are found at the deepest part of the epidermis (the top layer of the skin) and are thought to be very close and/or connected to nerve endings in the skin that are connected with our sensation of touch. These cells help us to sense light touch and to make out the details on an object’s surface. Merkel cells are a type of neuroendocrine cell which are cells found throughout the body. Neuroendocrine cells receive signals from the nervous system. In response, they produce hormones, which help the body regulate everything from breathing to digestion to heart rate. MCC is sometimes called neuroendocrine carcinoma of the skin.