Let’s talk about something important –Subungual Melanoma, or SM for short. SM is a type of malignant (cancerous) melanoma that occurs in the nails. Unlike melanoma on the skin, it is not caused by sun exposure. Instead, hurting your fingernails and toenails repeatedly increases your risk of developing SM.
You might notice SM when your nails start to change colour, usually brown or black. As it gets worse, your nail can start to hurt and might even be destroyed, which is typically quite painful. The main way to treat SM is to remove it with surgery. How deep they have to cut depends on how far the SM has grown.
The earlier we can find and treat SM, the better it is for the patient’s outcome. When SM is diagnosed at Stage 1A, there’s a good chance of surviving beyond 5 years – about 97% chance! But if SM is diagnosed at Stage 4, the chance of surviving beyond 5 years is only about 15-20%.
To find SM early, doctors use something called the ABCDEF guidelines. Yearly screenings are still the most effective method for clinicians to diagnose SM at an early state, leading to improved patient outcomes.
Now, you might be wondering how to spot SM. Because finding SM early makes a big difference, knowing the signs and telling SM apart from other nail problems is really important.
What does SM look like?
SM usually shows up as a black-brown streak or a strange colour on your nail bed. Here’s more about it:
- In most cases (75-90%), SM develops on the big toe or thumb.
- It often makes the nail look brown or black
- Sometimes, you might see a dark, up-and-down stripe on your fingernails or toenails.
- As it worsens, it can make your nail bed thick, painful, split, and damaged.
The Hutchinson Sign
The Hutchinson sign is a potential clue that someone might have SM. It shows up as an extension of brown-black colour near or on the fingernail or toenail. While this sign is valuable, it is not always a surefire way to tell if someone has melanoma.
What Can SM Be Mistaken For?
Sometimes, SM can look like other skin conditions, resulting in a delayed diagnosis and worse health outcomes. The information below can be helpful to consider when evaluating suspicious nail lesions. Still, it’s best to see a physician immediately if you notice anything unusual or concerning on your nails. Here are a few skin conditions SM is often mistaken for:
- Longitudinal Melanonychia (LM) LM presents itself as tan, brown, or black lines running from the bottom of your nail near your cuticle to the tip.LM always develops before the age of 50. The misdiagnosis of SM for LM results in a delayed SM diagnosis and poorer outcomes. Follow up on lesions appearing as LM for changes over time as these may indicate SM
- Onychomycosis is a fungus that infects nails, often your toenails, and causes them to change colour, become thicker, look strange, and even come off from the nail bed.
- Subungual Squamous Cell Carcinoma (SSCC) SSCC has a wide variety of way it presents itself on nails and skin including pain, sores, thicker skin on the outside called hyperkeratosis, rough nails with lines or ridges called nodular trachyonychia, dark lines on the nails called longitudinal melanonychia (LM), or red streaks in the nail called erythronychia.
Differentiating SM and Nail Trauma
SM can often be mistaken for a bruise, also known as subungual hematoma, which can result from nail trauma. But recognizing key differences between SM and nail trauma can guide you in deciding when to consult a physician for an assessment.
Nail trauma can take on different appearances based on how the injury happened. Generally, nail trauma shows up as a blue-black, reddish, or purple discolouration affecting either the entire or part of the nail.
Subungual melanoma (SM)
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Nail trauma
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Cause | Not directly linked to injury. | Directly linked to injury; however, patient may not always remember the injury. |
Pain | Not associated with pain. | May be associated with pain. |
Presentation over time | Lesions do not grow out with the nail over time. No clear proximal margin is visible. Lesions increase in size. | Clear proximal margin appears with the discoloured nail plate growing outwards. Lesions will completely disappear in up to 2-3 months for fingernails and nine months for toenails. |
Number of nails affected | Typically, it affects one nail at a time. | May affect multiple nails at a time. |
How to Identify SM
Screening remains the best way to diagnose SM and improve patient outcomes. Therefore, it’s essential to understand how to identify SM. To determine whether a pigmented nail lesion could be melanoma, you can use the ABCDEF guidelines.
A: Age – 50-70 years of age and African, Japanese, Chinese and Indigenous heritage.
B: Brown-black band – Greater than 3mm with an irregular border.
C: Change – Change in size and growth rate
D: Digit – Thumb, big toe, or index finger.
E: Extension – Extension of discolouration into the surrounding nail (Hutchinson sign).
F: Family history – Family history of melanoma or dysplastic nevi.
Prevention and Detection
Prevention and Detection
Did you know that 75% of melanomas are detected by patients themselves? Here are some steps you can take for prevention and early detection:
- Perform monthly self-exams: We encourage you to check your nails every month and report any new spots or changes to your doctor.
- Remove nail polish: Remember that nail polish can make it harder to spot any chance, so it’s a good idea to remove it before your self-exam.
- Avoid UV Nail Drying: Try other methods for taking care of your nails that don’t involve UV lamps. Some options include using press-on nails or regular nail polish. These methods are a safe and fun way to keep your nails looking great without any special equipment.
- Sun Protection: Protect your skin from harmful UV radiation by seeking shade, wearing protective clothing (including wide-brimmed hats and UV-protective sunglasses), and applying broad-spectrum sunscreen regularly.
Additionally, request a yearly skin examination from your physician. During this examination, your doctor will:
- Examine nail beds for discolouration.
- Use the ABCDEF guidelines when examining your finger and toenails.
Always keep in mind that early detection is key! Perform regular skin self-exams, familiarize yourself with the signs and characteristics of SM, and be on the lookout for any new growth or changes. If you notice something unusual, or if a spot doesn’t heal, it’s time to consult your dermatologist or family doctor.
For an accurate assessment, it is crucial to consult with a healthcare professional, preferably a dermatologist, for a thorough evaluation and proper diagnosis.
Watch our Melanoma Doesn’t Discriminate video